What is a consequence of CKD on the absorption of water-soluble vitamins?

Chronic kidney disease (CKD) can significantly impact the absorption of water-soluble vitamins, leading to deficiencies that often necessitate supplementation. As kidney function declines, the body’s ability to filter waste and manage nutrient balance is compromised. This reduced filtration can cause an accumulation of uremic toxins, impairing gastrointestinal function and leading to decreased absorption of essential nutrients, including water-soluble vitamins like vitamin C and the B vitamins.

Additionally, conditions commonly associated with CKD, such as reduced dietary intake, inflammation, and changes in metabolism, can further exacerbate the risk of vitamin deficiencies. For these reasons, individuals with CKD may require additional supplementation to meet their nutritional needs and prevent deficiencies that could lead to further health complications. Thus, acknowledging the need for supplementation is vital in the management and nutritional care of patients with chronic kidney disease.